The paper deals with hematological indices of lake frogs from two biotopes with different pollution types. The first biotope is the Chibi Canal, which receives water from rice bays, it is contaminated with pesticides. The second biotope is a reservoir near the old river-bed of the Kuban River near the forest park Krasny Kut. In both biotopes, no significant differences in the number of erythrocytes and hemoglobin in the blood of lake frogs were observed.